diff --git a/CHANGELOG.md b/CHANGELOG.md
index cea15ea61..f3c549170 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -14,6 +14,10 @@ The UserAction model, which was deprecated by the new change logging feature in
 
 Django 2.1 introduces view permissions for object types (not to be confused with object-level permissions). Implementation of [#323](https://github.com/digitalocean/netbox/issues/323) is planned for NetBox v2.6. Users are encourage to begin assigning view permissions as desired in preparation for their eventual enforcement.
 
+### upgrade.sh No Longer Invokes sudo
+
+The `upgrade.sh` script has been tweaked so that it no longer invokes `sudo` internally. This was done to ensure compatibility when running NetBox inside a Python virtual environment. If you need elevated permissions when upgrading NetBox, call the upgrade script with `sudo upgrade.sh`.
+
 ## New Features
 
 ### Patch Panels and Cables ([#20](https://github.com/digitalocean/netbox/issues/20))
@@ -34,6 +38,7 @@ NetBox now supports modeling physical cables for console, power, and interface c
 * [#2292](https://github.com/digitalocean/netbox/issues/2292) - Removed the deprecated UserAction model
 * [#2367](https://github.com/digitalocean/netbox/issues/2367) - Removed deprecated RPCClient functionality
 * [#2426](https://github.com/digitalocean/netbox/issues/2426) - Introduced `SESSION_FILE_PATH` configuration setting for authentication without write access to database
+* [#2594](https://github.com/digitalocean/netbox/issues/2594) - `upgrade.sh` no longer invokes sudo
 
 ## Changes From v2.5-beta2
 
diff --git a/upgrade.sh b/upgrade.sh
index 3a9f4a864..24e79f5bd 100755
--- a/upgrade.sh
+++ b/upgrade.sh
@@ -8,28 +8,19 @@
 PYTHON="python3"
 PIP="pip3"
 
-# Optionally use sudo if not already root, and always prompt for password
-# before running the command
-PREFIX="sudo -k "
-if [ "$(whoami)" = "root" ]; then
-	# When running upgrade as root, ask user to confirm if they wish to
-	# continue
-	read -n1 -rsp $'Running NetBox upgrade as root, press any key to continue or ^C to cancel\n'
-	PREFIX=""
-fi
-
+# TODO: Remove this in v2.6 as it is no longer needed under Python 3
 # Delete stale bytecode
-COMMAND="${PREFIX}find . -name \"*.pyc\" -delete"
+COMMAND="find . -name \"*.pyc\" -delete"
 echo "Cleaning up stale Python bytecode ($COMMAND)..."
 eval $COMMAND
 
 # Uninstall any Python packages which are no longer needed
-COMMAND="${PREFIX}${PIP} uninstall -r old_requirements.txt -y"
+COMMAND="${PIP} uninstall -r old_requirements.txt -y"
 echo "Removing old Python packages ($COMMAND)..."
 eval $COMMAND
 
 # Install any new Python packages
-COMMAND="${PREFIX}${PIP} install -r requirements.txt --upgrade"
+COMMAND="${PIP} install -r requirements.txt --upgrade"
 echo "Updating required Python packages ($COMMAND)..."
 eval $COMMAND