diff --git a/contrib/netbox.service b/contrib/netbox.service
index 3cd02d988..af6a6d988 100644
--- a/contrib/netbox.service
+++ b/contrib/netbox.service
@@ -12,7 +12,7 @@ Group=netbox
 PIDFile=/var/tmp/netbox.pid
 WorkingDirectory=/opt/netbox
 
-ExecStart=/opt/netbox/venv/bin/gunicorn --pid /var/tmp/netbox.pid --pythonpath /opt/netbox/netbox --config /opt/netbox/gunicorn.py netbox.wsgi
+ExecStart=/opt/netbox/venv/bin/uwsgi --ini /opt/netbox/netbox/local/uwsgi.ini
 
 Restart=on-failure
 RestartSec=30
diff --git a/docs/installation/4-uwsgi.md b/docs/installation/4-uwsgi.md
new file mode 100644
index 000000000..f90f9061a
--- /dev/null
+++ b/docs/installation/4-uwsgi.md
@@ -0,0 +1,59 @@
+# Gunicorn
+
+Like most Django applications, NetBox runs as a [WSGI application](https://en.wikipedia.org/wiki/Web_Server_Gateway_Interface) behind an HTTP server. This documentation shows how to install and configure [uWSGI](https://uwsgi-docs.readthedocs.io/en/latest/) (which is automatically installed with NetBox) for this role, however other WSGI servers are available and should work similarly well.  [gunicorn](http://gunicorn.org/) is a popular alternative.
+
+## Configuration
+
+NetBox ships with a default configuration file for uWSGI. To use it, copy `/opt/netbox/contrib/uwsgi.ini` to `/opt/netbox/uwsgi.ini`. (We make a copy of this file rather than pointing to it directly to ensure that any local changes to it do not get overwritten by a future upgrade.)
+
+```no-highlight
+sudo cp /opt/netbox/contrib/uwsgi.ini /opt/netbox/uwsgi.ini
+```
+
+While the provided configuration should suffice for most initial installations, you may wish to edit this file to change the bound IP address and/or port number, or to make performance-related adjustments. See [the uWSGI documentation](https://uwsgi-docs-additions.readthedocs.io/en/latest/Options.html) for the available configuration parameters.
+
+## systemd Setup
+
+We'll use systemd to control both uWSGI and NetBox's background worker process. First, copy `contrib/netbox.service` and `contrib/netbox-rq.service` to the `/etc/systemd/system/` directory and reload the systemd daemon.
+
+!!! warning "Check user & group assignment"
+    The stock service configuration files packaged with NetBox assume that the service will run with the `netbox` user and group names. If these differ on your installation, be sure to update the service files accordingly.
+
+```no-highlight
+sudo cp -v /opt/netbox/contrib/*.service /etc/systemd/system/
+sudo systemctl daemon-reload
+```
+
+Then, start the `netbox` and `netbox-rq` services and enable them to initiate at boot time:
+
+```no-highlight
+sudo systemctl enable --now netbox netbox-rq
+```
+
+You can use the command `systemctl status netbox` to verify that the WSGI service is running:
+
+```no-highlight
+systemctl status netbox.service
+```
+
+You should see output similar to the following:
+
+```no-highlight
+● netbox.service - NetBox WSGI Service
+     Loaded: loaded (/etc/systemd/system/netbox.service; enabled; vendor preset: enabled)
+     Active: active (running) since Mon 2021-08-30 04:02:36 UTC; 14h ago
+       Docs: https://docs.netbox.dev/
+   Main PID: 1140492 (uwsgi)
+      Tasks: 19 (limit: 4683)
+     Memory: 666.2M
+     CGroup: /system.slice/netbox.service
+             ├─1140492 /opt/netbox/venv/bin/python3 /opt/netbox/venv/bin/uwsgi --pid /va>
+             ├─1140513 /opt/netbox/venv/bin/python3 /opt/netbox/venv/bin/uwsgi --pid /va>
+             ├─1140514 /opt/netbox/venv/bin/python3 /opt/netbox/venv/bin/uwsgi --pid /va>
+...
+```
+
+!!! note
+    If the NetBox service fails to start, issue the command `journalctl -eu netbox` to check for log messages that may indicate the problem.
+
+Once you've verified that the WSGI workers are up and running, move on to HTTP server setup.
diff --git a/docs/installation/index.md b/docs/installation/index.md
index 6ad4aa79e..25cfd5143 100644
--- a/docs/installation/index.md
+++ b/docs/installation/index.md
@@ -12,7 +12,7 @@ The following sections detail how to set up a new instance of NetBox:
 1. [PostgreSQL database](1-postgresql.md)
 1. [Redis](2-redis.md)
 3. [NetBox components](3-netbox.md)
-4. [Gunicorn](4-gunicorn.md)
+4. [uWSGI](4-uwsgi.md)
 5. [HTTP server](5-http-server.md)
 6. [LDAP authentication](6-ldap.md) (optional)